Basic Information
VIS ID
TVIS20002765
Fusion event
HPV-TCERG1L integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
132973387/131175124 (Hg38)
End
132973387/131175124 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
TCERG1L
Nearest miRNA
hsa-mir-107/Upstream/212456; hsa-mir-202/Downstream/2072387;
Nearest TSS
ENST00000439456/Upstream/79906; ENST00000634373/Downstream/85212;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/79699, chr10-CpG: 25/Downstream/84951
Upstream sequence
CTACTGTccccttatccatggttttgctttttgtggtttcagttacctgtagtcaaccacagtctgaaaatattaaggtattttaagacagaaagagaga
Downstream sequence
gaggagagaaaccgcattcacgtaagttttattccagcatattgttataattcttctattttattattagttattgttgctaatcttttactgtgcctaa
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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