Basic Information
VIS ID
TVIS20002766
Fusion event
HPV-chr11:p15.1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
16692937/16671390 (Hg38)
End
16692937/16671390 (Hg38)
Fragile sites / regions
FRA11C ; FRA11I
Nearest miRNA
hsa-mir-210/Upstream/701769; hsa-let-7a-2/Downstream/1716397;
Nearest TSS
ENST00000527297/Upstream/58258; ENST00000525106/Downstream/67011;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/56968, chr11-CpG: 36/Downstream/67008
Upstream sequence
ttcctcttttcctaattgaataccctttatttccttctcctgcctgattgccctggccagaacttccaacactatgttgaataggagtggtgagagagta
Downstream sequence
catccctgtcttgtggcagttttcaaagggaatgcttccagtttttgcccattcagtatgatattggctgtgggtttttcatagatagctcttattattt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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