Basic Information
VIS ID
TVIS20002769
Fusion event
HPV-LOC105369496 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
112570750/112700027 (Hg38)
End
112570750/112700027 (Hg38)
Location type
Intronic
Target gene
LOC105369496
Nearest miRNA
hsa-mir-10392/Upstream/1186512; hsa-let-7a-2/Downstream/749996;
Nearest TSS
ENST00000527297/Upstream/144225; ENST00000524772/Downstream/87277;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/409549, chr11-CpG: 178/Downstream/261775
Upstream sequence
tttagcttttgataaatgtgatttgtctagctgtggacttctctgagtttaacctacttggattaggttgagcctcatagacatgtatgttaaaaaattt
Downstream sequence
tgtcaaatttgtgaatcttttggtcattaattcatcaaatatttttttctgtccctttctttctcttctctttttctgagatttttcttatgcatatact
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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