Basic Information
VIS ID
TVIS20002771
Fusion event
HPV-chr11:q24.1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
123083909/123213201 (Hg38)
End
123083909/123213201 (Hg38)
Nearest miRNA
hsa-let-7a-2/Upstream/1060893; hsa-mir-3167/Downstream/168239;
Nearest TSS
ENST00000527297/Upstream/17920; ENST00000533341/Downstream/101566;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/16923, chr11-CpG: 54/Downstream/88545
Nearby gene
LOC105369539(-5417) ;
Upstream sequence
catgacagtcgtataaggcatatagaaatatccccattttacaaattaaaaactgggtagcatctctgggttgcttagcttgtgagtggaagagtcagca
Downstream sequence
tccaatcaggtctgtaggatcccagagcatgccccatctaccactaaattaagctgTTGGagagcataggttttgaaacgtggcagatctgagtgtgaat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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