Basic Information
VIS ID
TVIS20002776
Fusion event
HPV-chr14:q11.2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23809235/23340026 (Hg38)
End
23809235/23340026 (Hg38)
Nearest miRNA
hsa-mir-4707/Upstream/382997; hsa-mir-1185-1/Downstream/48570;
Nearest TSS
ENST00000550708/Upstream/16581; ENST00000554010/Downstream/8195;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/17914, chr14-CpG: 18/Downstream/6651
Nearby gene
SLC22A17(+6278) ;
Upstream sequence
CCTTCACCGGATCAGCTGTTCATCGCCATCCACCGGTTCACTCCTGCACTCGTGTGCTCACTCTCTCACTCCTCAGTGCCTCGCCTGCTTATCCACATAC
Downstream sequence
ttcccctgggcttttcatgctctctctcttgctagctgccatttaagacgtgcctgctttcccttccaccatgattgtaagtttcctgaggcctctccag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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