Basic Information
VIS ID
TVIS20002786
Fusion event
HPV-LINC01954 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
11020185/10880059 (Hg38)
End
11020185/10880059 (Hg38)
Location type
Intronic
Target gene
LINC01954
Nearest miRNA
hsa-mir-4261/Upstream/687388; hsa-mir-10b/Downstream/660546;
Nearest TSS
ENST00000437798/Upstream/1790; ENST00000295082/Downstream/31878;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/66801, chr2-CpG: 140/Downstream/31916
Upstream sequence
gaggctgaatcagactggaagagtctgggtcacgctgggtcatggctctaagTCCTGGCTTCAAGGCGGGATAAAAAATCAAGCACTGGCggtcgggcgt
Downstream sequence
gtttcattctttctttgctttgctgggcgttttgtccaattcttcgttcaaaaagccaagaacctggacagcttgccgtcacgaccctctagtggtaaca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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