Basic Information
VIS ID
TVIS20002795
Fusion event
HPV-LOC105372714 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
31738626/33150820 (Hg38)
End
31738626/33150820 (Hg38)
Location type
Intronic
Target gene
LOC105372714
Nearest miRNA
hsa-mir-103a-2/Upstream/912973; hsa-mir-1-1/Downstream/898299;
Nearest TSS
ENST00000382410/Upstream/46116; ENST00000253362/Downstream/10948;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/330502, chr20-CpG: 30/Downstream/250518
Upstream sequence
ccctgggcaagtggctacccttctctgagcctcagttttctcatctgtaaatgggactgatattgcttcaccacatatattctgaagattcataagataa
Downstream sequence
TAGTTTACACCTGTGGAAGATGAAGATTTGCATTGTGTTACAAATTCTGATAGAATCATTTAATCTCATCTGATAAATTTATTCTTCAAAGAGAAAGGCA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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