VISDB Viral Integration Site DataBase

VIS ID

TVIS20002802

Fusion event

HPV-ACVR2B integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Squamous-cell carcinoma (SCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HPV

Subtype

HPV16

Reference genome

Chromosome

chr3

Cytoband

p22.2

Reference genome

Start

End

38513823/38472332 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-215-5p ; hsa-mir-194-5p ; hsa-mir-141-3p ; hsa-mir-200c-3p ; hsa-mir-335-5p ; hsa-mir-140-3p ; hsa-mir-103a-3p ; hsa-mir-101-3p ; hsa-mir-221-3p ; hsa-mir-107 ; hsa-mir-4310 ; hsa-mir-4326 ; hsa-mir-3927-3p ; hsa-mir-4451 ; hsa-mir-6831-5p ; hsa-mir-7157-5p ; hsa-mir-29b-1-5p ; hsa-mir-134-3p ; hsa-mir-1304-5p ; hsa-mir-7114-5p ; hsa-mir-7854-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-4761-5p ; hsa-mir-4464 ; hsa-mir-4748 ; hsa-mir-6867-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4666a-3p ; hsa-mir-577 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-203a-3p ; hsa-mir-5087 ; hsa-mir-6134 ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-4799-5p ; hsa-mir-545-5p ; hsa-mir-4282 ; hsa-mir-6516-5p ; hsa-mir-3685 ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-329-5p ; hsa-mir-384 ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-944 ; hsa-mir-369-3p ; hsa-mir-5571-5p ; hsa-mir-574-5p ; hsa-mir-2054 ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-6749-3p ; hsa-mir-126-3p ; hsa-mir-361-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-190a-3p ; hsa-mir-23b-3p ; hsa-mir-297 ; hsa-mir-511-3p ; hsa-mir-567 ; hsa-mir-6509-5p ; hsa-mir-6800-5p ; hsa-mir-6802-5p

Nearest miRNA

hsa-mir-12127/Upstream/502852; hsa-let-7g/Downstream/665874;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/16672, chr3-CpG: 39/Downstream/23859

Upstream sequence

ACAATACATGTCCCGTGTGGTCACTGTAAGCATTAAATATCAATCAGAAGAGAGTGCTTTTAAATAGGGAGGGAAAAAATCCATTTGTTGGGGCTATAAT

Downstream sequence

GGCTGCCTTTCGAGGGGTGCTGTCTGTGGGGAGAGCTGCCTTTCCTCTCTGGGCAGATGTGAAGGCTGGACACCAGAGGGAGAACACTGGCCCTCCTGAG