Basic Information
VIS ID
TVIS20002811
Fusion event
HPV-chr4:q26 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
120795792/119874637 (Hg38)
End
120795792/119874637 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/5217783; hsa-mir-1305/Downstream/5632622;
Nearest TSS
ENST00000502981/Upstream/70122; ENST00000505122/Downstream/64903;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/245542, chr4-CpG: 54/Downstream/191825
Upstream sequence
TGTGTGGAGACTGTAGGGTGAGAGCACACAATTATTAGCATCATTTCTGAGTGATCTCACAGATTTTTTTTCTTGTGTTTGCTTTGCTTTTTGACAACTG
Downstream sequence
AAATATGTGTTTTCCTTTCTGTATTGAAATCTCTAATTCATTTTCCATACTCCCATAATCTTATGTAACAAAGTAGATAAGTATTCCaattttatatttt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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