Basic Information
VIS ID
TVIS20002829
Fusion event
HPV-chr5:q34 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
End
165015321/165588316 (Hg38)
Nearest miRNA
hsa-mir-10397/Upstream/5102866; hsa-mir-103a-1/Downstream/2577529;
Upstream sequence
GACTGAAAGTCCACCACATTCCCATGTCTTGCTTAGTAGCAAGAAATAAAAGAAACATTTAAAAGGAGAGATAATATTTGTTCTGTGTCTGCTATGTGAC
Downstream sequence
AAAAAGCATAGAGCAGTTGTCCCATagtcggctccttggtatctgcaggggattggttccagaggccctgtggataccaaaatctatgtttgctcaagtc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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