Fusion event
HPV-chr5:q34 integration
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
End
165015321/165588316 (Hg38)
Nearest miRNA
hsa-mir-10397/Upstream/5102866; hsa-mir-103a-1/Downstream/2577529;
Upstream sequence
GACTGAAAGTCCACCACATTCCCATGTCTTGCTTAGTAGCAAGAAATAAAAGAAACATTTAAAAGGAGAGATAATATTTGTTCTGTGTCTGCTATGTGAC
Downstream sequence
AAAAAGCATAGAGCAGTTGTCCCATagtcggctccttggtatctgcaggggattggttccagaggccctgtggataccaaaatctatgtttgctcaagtc
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.