Basic Information
VIS ID
TVIS20002836
Fusion event
HPV-chr6:p25.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr6
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
1404906/1404671 (Hg38)
End
1404906/1404671 (Hg38)
Nearest miRNA
hsa-mir-6720/Upstream/14260; hsa-mir-10398/Downstream/1449360;
Nearest TSS
ENST00000381078/Upstream/14837; ENST00000628509/Downstream/124240;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/10736, chr6-CpG: 27/Downstream/110609
Nearby gene
FOXF2(-9074) ;
Upstream sequence
GGTAGTTCTTAATCCTAGATACATTTCAGAATCACTCATGGCACTCGTTTTAAACAGACTGCCAGACCAAACCTCAAATCCACtggcaaagactgctaat
Downstream sequence
ACACACACTAAAGATAATGTCCCAGAGATGGCTGTGGGCTGTCTCCCGCCCACAGCCCCAGGAGTCCCTTCCAGATAGCAGCCCTGAAGAGGCTATGGCC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate