Basic Information
VIS ID
TVIS20002840
Fusion event
HPV-chr6:q14.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
87625825/86916107 (Hg38)
End
87625825/86916107 (Hg38)
Nearest miRNA
hsa-mir-10398/Upstream/8376798; hsa-mir-1202/Downstream/3396635;
Nearest TSS
ENST00000381078/Upstream/1272315; ENST00000305344/Downstream/21199;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1236667, chr6-CpG: 43/Downstream/21428
Upstream sequence
agaaagaggattgcctgagctcaggagttcaaggtttcagtaagctattattgtaccactgtactccagcatgggctgagtgagacctcgttgccaaaaa
Downstream sequence
aatatgaccttgagcaatgtattaccctttttggccttggtttccttatcataaaatgaagttaataaaagataacaagaatttcctctgggtgtccttg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate