Basic Information
VIS ID
TVIS20002841
Fusion event
HPV-chr7:p15.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
21182812/21143193 (Hg38)
End
21182812/21143193 (Hg38)
Nearest miRNA
hsa-mir-1302-6/Upstream/1437757; hsa-mir-10399/Downstream/327865;
Nearest TSS
ENST00000635602/Upstream/307762; ENST00000440636/Downstream/284841;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/344608, chr7-CpG: 104/Downstream/283835
Upstream sequence
AACAAGTGTGCTTTCCCACTCTATTATGGACATTCAGTCCTTAGATAAAATCTAACTAGTTAATTATGTCATGGGCTTCTTTTGTTTTAAATATGACGTT
Downstream sequence
TACCTAGGTTGCTGAAAAGGAGTTGAAAATTGACTTGAATGCATGTGGAGGTCCTGTATTTGAAAACGTTTGGCACAATTTGGGAATGATGTACGGCTTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate