Basic Information
VIS ID
TVIS20002843
Fusion event
HPV-chr7:p12.2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr7
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
49792063/49752467 (Hg38)
End
49792063/49752467 (Hg38)
Nearest miRNA
hsa-mir-1183/Upstream/4870667; hsa-mir-10399/Downstream/7203318;
Nearest TSS
ENST00000635602/Upstream/522330; ENST00000340652/Downstream/21194;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/827715, chr7-CpG: 249/Downstream/20945
Upstream sequence
CTGTATATCTCAGGTTTTTAAATAGTTATTCTTCTTATCACCTTGTATATATATTAGACTTCAACATATTTTAGGCCAATTTCGTTTAGACTTGGATTGG
Downstream sequence
GGCCACACGTGTGGCTCCTGAATACCGTTGGCCTAACTTCCTCTGGAGCTCTGTGGGGTCTTTTGGTTCTGGGAAAGAAAAGGTACAACTAAAGACCCTG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate