Basic Information
VIS ID
TVIS20002847
Fusion event
HPV-LOC105375411 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
96088452/96459140 (Hg38)
End
96088452/96459140 (Hg38)
Location type
Intronic
Target gene
LOC105375411
Nearest miRNA
hsa-mir-10525/Upstream/239384; hsa-mir-10399/Downstream/1504518;
Nearest TSS
ENST00000635602/Upstream/136993; ENST00000555308/Downstream/37202;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/136816, chr7-CpG: 38/Downstream/250364
Upstream sequence
GGGGAACAGGGGTGGCATCCCTGGCCTGTCACGTTCTGTCCTCTATCTGAACTTGAAAACCAAGGGACCCTCCTGCCTCGGCAGAGCTGACCTCAGGACG
Downstream sequence
catggaagttaaagataggattttacaaggatagagtgacagaaggatgtgggacaaggttgtggggaagagtgttaaagagggatgacacgatggatca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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