Basic Information
VIS ID
TVIS20002853
Fusion event
HPV-chr9:q21.13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr9
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
74182512/71567596 (Hg38)
End
74182512/71567596 (Hg38)
Nearest miRNA
hsa-mir-101-2/Upstream/757512; hsa-let-7a-1/Downstream/12402152;
Nearest TSS
ENST00000422679/Upstream/120692; ENST00000473252/Downstream/119832;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/120415, chr9-CpG: 137/Downstream/200565
Upstream sequence
CACCTGGAGGACCTTCAGGTCCCGCAGCTGGAGCAGAAGAACTGTCCTCTGCTCCACACTGGAAAGGCAGGATGTGTACTTTTTACTCTTGTGAAGTCCA
Downstream sequence
tcaaaagaaaggttcaactctgtcagttgagtacacacatcacaaacaagtttctgagaatgcttctgtctagtttttatgggaagatatttcctttttc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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