Basic Information
VIS ID
TVIS20002859
Fusion event
HPV-DIAPH2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chrX
Cytoband
q21.33
Reference genome
End
96107808/96852809 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/1789583; hsa-mir-105-1/Downstream/9787005;
Upstream sequence
CAACAACAATaacaatggtgcttcacattaatcgaatacttattacctgctgaacactgttttgaagtgcctttagttcatgaactaatttaattctcac
Downstream sequence
ACCATTTGGCAAATAGTCTTTTCTGCGACTACATCAAGAGTCCCTGTTGTCAAAGAAATGCCTTAGCAAATGGAAGATATAAATAATACCTTTACCAAGT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate