Basic Information
VIS ID
TVIS20002900
Fusion event
HPV-LOC107986315 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr4
Cytoband
q28.3
Reference genome
GRCh37/hg19
Start
138874866/137953712 (Hg38)
End
138874866/137953712 (Hg38)
Location type
Intronic
Target gene
LOC107986315
Nearest miRNA
hsa-mir-12113/Upstream/12446405; hsa-mir-1305/Downstream/5389748;
Nearest TSS
ENST00000502981/Upstream/146006; ENST00000502757/Downstream/95860;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1141124, chr4-CpG: 21/Downstream/606868
Upstream sequence
ATTTAAATGTGCATGCATAAAAAGTAACTCAAAGGTTTTCCACTAGGAGATATTGCAGTGGAACGAATTGTACTGCATGAACTTCCTGAAACAAAATTGT
Downstream sequence
TATTGAAATTGAGAGAATTCTAGATGAGAAATATTGGGGAAGATGAAGAGAGGTACAGAGTACAGAAGAGGAGCATGACCCTGAGGTCCCTGGAATGGCT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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