Basic Information
VIS ID
TVIS20002934
Fusion event
HPV-LOC105374313 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr3
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
149842636/150124849 (Hg38)
End
149842636/150124849 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
LOC105374313
Nearest miRNA
hsa-let-7g/Upstream/15686943; hsa-mir-1224/Downstream/1441027;
Nearest TSS
ENST00000440867/Upstream/26817; ENST00000472890/Downstream/100341;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/73967, chr3-CpG: 17/Downstream/56459
Upstream sequence
catcatgtgccaggcactttacagacgttatctctggttcacatccttctttctaagatgagaaagcagacattaagggacatacctaaagatacacaga
Downstream sequence
CTCTAATGTTAAATTTAAAAAAAAAAAGAGTTTGACAGGTAATAATTTGTTTTGCATGACTTTCTCCCTTTATTTTCTCTGCACGCAGGTCTAACCATAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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