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VISDB
Viral Integration Site DataBase
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TVIS20003068
Basic Information
VIS ID
TVIS20003068
Fusion event
HPV-RABGAP1L integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;EU918767.1
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
174313760/174344622 (Hg38)
End
174313760/174344622 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1G
Target gene
RABGAP1L
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-4504
;
hsa-mir-4778-3p
;
hsa-mir-676-5p
;
hsa-mir-4714-3p
;
hsa-mir-34c-3p
;
hsa-mir-7161-3p
;
hsa-mir-3156-5p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-3187-3p
;
hsa-mir-4435
;
hsa-mir-588
;
hsa-mir-4701-5p
;
hsa-mir-548s
;
hsa-mir-378a-5p
;
hsa-mir-6802-5p
;
hsa-mir-6800-5p
;
hsa-mir-6131
;
hsa-mir-4755-3p
;
hsa-mir-6759-3p
;
hsa-mir-3663-5p
;
hsa-mir-3653-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-4781-3p
;
hsa-mir-5089-5p
;
hsa-mir-6807-5p
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-6778-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-150-5p
;
hsa-mir-1224-3p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-6504-3p
;
hsa-mir-512-3p
;
hsa-mir-576-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-1297
;
hsa-mir-1343-3p
;
hsa-mir-1976
;
hsa-mir-23a-5p
;
hsa-mir-23b-5p
;
hsa-mir-26a-5p
;
hsa-mir-26b-5p
;
hsa-mir-4279
;
hsa-mir-4465
;
hsa-mir-4722-3p
;
hsa-mir-4740-3p
;
hsa-mir-6513-3p
;
hsa-mir-660-3p
;
hsa-mir-6727-3p
;
hsa-mir-6742-3p
;
hsa-mir-6747-3p
;
hsa-mir-6783-3p
;
hsa-mir-6791-3p
;
hsa-mir-6829-3p
;
hsa-mir-6836-3p
;
hsa-mir-6852-5p
;
hsa-mir-8062
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2199978; hsa-mir-1182/Downstream/1623748;
Nearest TSS
ENST00000473358/Upstream/69522;
ENST00000367685/Downstream/20608;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/184713
,
chr1-CpG: 121/Downstream/654731
Upstream sequence
AAGGCCATGTTTGCTATAGATGTTAGGCAGTGAGCTCAGGTTTACATTTCAGTTTTGTTTGTTTTCACAGCCCCCAAGCCCTAATCATTTTCTACCATAC
Downstream sequence
CCATACTACCACATTTCTCTGTTGTCATTACACTGAGCTAAATTAATTTACCTCCCTGTCCAAATTGTAAGCCTACAGAGTTAGAATCTACCCAGGAAAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Sample Information
×
Sample name
T7745
Sample type
Tumor
Gender
Female
CpG Island Information
×
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