Basic Information
VIS ID
TVIS20003071
Fusion event
HPV-MAML3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;EU918767.1
Host Sequence
Chromosome
chr4
Cytoband
q31.1
Reference genome
End
140820872/139899718 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/14392411; hsa-mir-1305/Downstream/3443742;
Upstream sequence
TTCTTTCTGCTATGGTTCACATTTAAAACTCTATTCCCAAAAAGTCTTGGAAGTACATAAGGCTGATGGTGCCTCTTTTCAATGTTTGGAACATGAGCAC
Downstream sequence
TCCTAACATTACTTAGACAGAAAACAACTTTACTCTCTATGAGTAAATGAATTTGAATTTTAAAATTATGTATATAATCTGTATATATCACATATAATAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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