Basic Information
VIS ID
TVIS20003091
Fusion event
HPV-COL24A1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
86243162/85777479 (Hg38)
End
86243162/85777479 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
COL24A1
Nearest miRNA
hsa-mir-101-1/Upstream/643606; hsa-mir-11399/Downstream/580153;
Nearest TSS
ENST00000473358/Upstream/32730; ENST00000490884/Downstream/379284;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/68909, chr1-CpG: 40/Downstream/378116
Upstream sequence
GCATGGGGTCGCAGACAGGTGACTTGTTCTGTCTGCGGAATAATCAGCTGTAAGCTTCTCATTTTTACTGAATCAGGGGTTTCAAGGCTGGTAAGGTCAA
Downstream sequence
ACAATTCCTTCTTTGGTTTCAAAGACCACATCTAAGAGAAGTCTATCTTCTGGAAAGAAATTTCCTCAAAAATATTTTCATAACCTTATTTAATAAGCAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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