Basic Information
VIS ID
TVIS20003099
Fusion event
HPV-BTBD10 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
13411485/13389938 (Hg38)
End
13411485/13389938 (Hg38)
Location type
Intronic
Target gene
BTBD10
miRNAs that regulate target gene
hsa-mir-340-5p ; hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-328-3p
Nearest miRNA
hsa-mir-210/Upstream/1226171; hsa-let-7a-2/Downstream/2579595;
Nearest TSS
ENST00000527297/Upstream/14259; ENST00000532769/Downstream/50270;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/110892, chr11-CpG: 82/Downstream/72788
Upstream sequence
ttcctattcaacatagtactagaaggcctagctagagcaagcaagtatgataatcaaataaaaggcatccagatatgaaaagaggaagtcaaactatctg
Downstream sequence
ttttatcattgtctcatcttatgtcttggaatacctaaagatgacaataaaaacttttagacctagcaaatttagtaaaattgcaggatacaatattatt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate