Basic Information
VIS ID
TVIS20003101
Fusion event
HPV-LOC105369468 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
105375790/105505063 (Hg38)
End
105375790/105505063 (Hg38)
Location type
Intronic
Target gene
LOC105369468
Nearest miRNA
hsa-mir-10392/Upstream/1655083; hsa-let-7a-2/Downstream/5842694;
Nearest TSS
ENST00000527297/Upstream/365337; ENST00000527177/Downstream/26634;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1340733, chr11-CpG: 31/Downstream/105336
Upstream sequence
ggccggggcaggcggatcacctgaggccaggagttcgagaccagcccgaccaacatggagaaaccctgtctctacaaaaaatacaaaaattagccaggtg
Downstream sequence
tggtagcacatgcctgtaatcctagctactcgggaggttgaggcaggagaattgcttgaacccgggaggtggaggttgcagtgagccgagattgtggcat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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