Basic Information
VIS ID
TVIS20003143
Fusion event
HPV-LOC101928923 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
156605243/156284109 (Hg38)
End
156605243/156284109 (Hg38)
Location type
Intronic
Target gene
LOC101928923
Nearest miRNA
hsa-mir-10398/Upstream/337230; hsa-mir-1913/Downstream/495569;
Nearest TSS
ENST00000381078/Upstream/828206; ENST00000637910/Downstream/214857;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/969361, chr6-CpG: 41/Downstream/112828
Upstream sequence
CACAAAAATACCGATTTGATAGCTGATGGCAAGTTTTGTTTCAGCTGATGTTTGAAACATGCTGGAAAATGCAATCTTGCTAAGCAAGGAAAGCAAAACC
Downstream sequence
atcacaggcacccaataaatatttgttcaatTGTTTTGTTCTAAAGTATCTCTCTTCAATGTTAATGAGATTAAATGACACCAAAAGTCCAAAGAAAACC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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