Basic Information
VIS ID
TVIS20003156
Fusion event
HPV-BRINP1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
122103146/119340868 (Hg38)
End
122103146/119340868 (Hg38)
Location type
Intronic
Target gene
BRINP1
Nearest miRNA
hsa-let-7a-1/Upstream/5131339; hsa-mir-12126/Downstream/904111;
Nearest TSS
ENST00000422679/Upstream/131982; ENST00000565320/Downstream/28557;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1595504, chr9-CpG: 97/Downstream/27940
Nearest cancer related gene
BRINP1(TSG, No orient, 0)
Upstream sequence
ttttatattttttgtagagatgggatttcaccatgctgcccaggctggtctcaaactcctgggctcaagcaatctgcctgcttcggcccctcaaagtgct
Downstream sequence
GCTCTGACATATGTGAACAAGTTACTTTTATTTTGTTATTTTGTTAGTAGTTATGTTTTATTCTCACAAGTTTAGATTCTAACTTGGTAATGTGTTATAG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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