Basic Information
VIS ID
TVIS20003162
Fusion event
HPV-LOC102724900 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
AY262282.1
Host Sequence
Chromosome
chr22
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
27731046/27335085 (Hg38)
End
27731046/27335085 (Hg38)
Location type
Intronic
Target gene
LOC102724900
Nearest miRNA
hsa-mir-1286/Upstream/779762; hsa-let-7a-3/Downstream/585440;
Nearest TSS
ENST00000624155/Upstream/3298; ENST00000422833/Downstream/80120;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/577915, chr22-CpG: 16/Downstream/103379
Upstream sequence
TGTGATCTGTCATCTCAGTATTCTGGGAAGATGGCATCTGGTTGGCGAATAGGAATAGCAAGAGGAGGTATAGGGGGCACATACTGGAGAAGACCATGGT
Downstream sequence
GGGGGCAGGAGGTGGGTGGCCATTGAGGTCTGTGTACAAATATTCCATCTCTCCTCCCTCCATTTGGAACAGAAGTGGAGAGTATGAACATAAGCAagag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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