Basic Information
VIS ID
TVIS20003176
Fusion event
HPV-chrX:q26.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
134177877/135043847 (Hg38)
End
134177877/135043847 (Hg38)
Nearest miRNA
hsa-let-7f-2/Upstream/497136; hsa-mir-105-1/Downstream/1507031;
Nearest TSS
ENST00000429181/Upstream/11465; ENST00000608079/Downstream/8243;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/10892, chrX-CpG: 76/Downstream/7686
Nearby gene
LOC112268301(-3489) ; RTL8A(+7085) ;
Upstream sequence
gtatcacttgatcctaggagttcgaggccagtgtaggcaatatggcgagatgctgtctctattaaaaaaaaaaaaagaaagaaaattagccagacatggt
Downstream sequence
ttttgtggttccatagaaattttagaatagatttttctagttctgtgaaaaatgtcattggtagtttgataggaatagcattgaatctttaaattgcttt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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