Basic Information
VIS ID
TVIS20003178
Fusion event
HPV-chr1:q25.2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1;HQ537751.1
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
176429272/176460136 (Hg38)
End
176429272/176460136 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/491657; hsa-mir-1182/Downstream/569227;
Nearest TSS
ENST00000473358/Upstream/252488; ENST00000493665/Downstream/3035;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/252461, chr1-CpG: 44/Downstream/704120
Nearby gene
PAPPA2(+3023) ;
Upstream sequence
AGCTAGTAAAACTCACCGCTTTACTCGTAGACATCTAATTTTGCACAGACTGGGAAGCGTCATCAGGTGTGAAGTTGCCTTGATGCAAATTTAAATCATT
Downstream sequence
GCAATTTTCTTTATTCAATGGTCAAATACTTCATCATTAGTGGAGTATTCTACTATTTCTGCCTGTTTTCTGTTTCTCATTACCATCAAATGTGTATTTA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate