Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene818632508345501285627922836436028372539083722293837263208371075883712045837133188371443283720898837215678371745483717987837450458374541683745586
Basic Information
VIS ID
TVIS20003179
Fusion event
HPV-DLG2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1;HQ537751.1
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
83456629/83745586 (Hg38)
End
83456629/83745586 (Hg38)
Location type
Intronic
Target gene
DLG2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10392/Upstream/1854750; hsa-let-7a-2/Downstream/2532747;
Nearest TSS
ENST00000527297/Upstream/20183; ENST00000534275/Downstream/421416;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/459093, chr11-CpG: 24/Downstream/1882713
Upstream sequence
accaatgtttgccaggctagtcttgaactcctgacctcaagtgatctctctgccagagcctcccaaagtgctagaattacaggcatgagccaccatgccc
Downstream sequence
gacctaaattcttcaaaatttttgaacaaaggcctctgaattttttttgcactgggtccagcaaattgtgtagttgattctgtctccaggataataaata
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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