Basic Information
VIS ID
TVIS20003180
Fusion event
HPV-SUCLG2P3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1;HQ537751.1
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
107457397/107586671 (Hg38)
End
107457397/107586671 (Hg38)
Location type
Intronic
Target gene
SUCLG2P3
Nearest miRNA
hsa-mir-10392/Upstream/3736691; hsa-let-7a-2/Downstream/3761086;
Nearest TSS
ENST00000527297/Upstream/20925; ENST00000529675/Downstream/4420;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/128706, chr11-CpG: 72/Downstream/4422
Upstream sequence
ttatctctcctgactgttcttttccaaaccattcaaaaaacaaataaaataagacctggaattgattctcattagctccaactggacggatttgagctga
Downstream sequence
atgcccgtgtccctgagccaacaactgttctgatgttctcatcagccaggcttgggtcagaagtttccttaagtactccagaggtacctggagatgcaag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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