Basic Information
VIS ID
TVIS20003227
Fusion event
HPV-CPVL integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1;HQ537751.1
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
29059388/29019772 (Hg38)
End
29059388/29019772 (Hg38)
Location type
Intronic
Target gene
CPVL
Nearest miRNA
hsa-mir-1183/Upstream/1850209; hsa-mir-10399/Downstream/660962;
Nearest TSS
ENST00000635602/Upstream/10846; ENST00000416513/Downstream/52073;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/60847, chr7-CpG: 115/Downstream/174583
Upstream sequence
aataatgtttagcaggaaatttgtagctttaaatgtttggattaaaaaagaggGTTAggccggtcgtggtggctcacgcctgtaatcccagcactttggg
Downstream sequence
TTTTCCCTCCTCATAACCCTCATCTCCACAAACCACCCCAAACCAACGCTGAGGCACTAAGGGGGAAGGATCTTTGCCAACATTTTAAAATCACCTATAC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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