Basic Information
VIS ID
TVIS20003228
Fusion event
HPV-SNTG1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537687.1;HQ537751.1
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
51482096/50569536 (Hg38)
End
51482096/50569536 (Hg38)
Location type
Intronic
Target gene
SNTG1
miRNAs that regulate target gene
hsa-mir-2681-5p ; hsa-mir-548c-3p ; hsa-mir-7977 ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-3671 ; hsa-mir-6849-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p
Nearest miRNA
hsa-mir-124-1/Upstream/7673261; hsa-mir-10400/Downstream/11145252;
Nearest TSS
ENST00000518652/Upstream/16486; ENST00000642377/Downstream/74305;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/659236, chr8-CpG: 98/Downstream/839066
Upstream sequence
AGAATATAAAATCTGGTTCCTCAGCAGCTATCTTTCTACCATAAGGAGGGCAATTTGTCTGAGAAGGTGATTACCTTAGACTAGCAAACGAAAGACAGAG
Downstream sequence
caaacaaaaaacaaaaaaaaaacCTTCTATTCTGTCTGCCACATTGAAAAGGCTCAACAAAGCTTGTAGGTGAATTGAAAATCATGATGGAATAAAGACT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate