Basic Information
VIS ID
TVIS20003322
Fusion event
HPV-LOC105373186 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV18
Reference genome
AY262282.1
Host Sequence
Chromosome
chrX
Cytoband
p11.3
Reference genome
GRCh37/hg19
Start
42596234/42736983 (Hg38)
End
42596234/42736983 (Hg38)
Location type
Intronic
Target gene
LOC105373186
Nearest miRNA
hsa-mir-1587/Upstream/2899370; hsa-let-7f-2/Downstream/3009174;
Nearest TSS
ENST00000429181/Upstream/280405; ENST00000440955/Downstream/41264;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/812978, chrX-CpG: 34/Downstream/40774
Upstream sequence
GAAGGCCAGGTCCACTGAACAAATGGAATTTATTCTGTCCTCCCAGTGGGCCTAGGAAGATTCGGTTTGTCCTAGAATAACCTACAGGTCCCACAGTGAT
Downstream sequence
AAATAAAAGAAGTGCTTACAATCATTTAATGGAAATAGGAGTGAATGCTGTTAAGATGTGCTACGTGGTGCTGAGCAAATCTTTGACTTATCATCATGCT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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