Basic Information
VIS ID
TVIS20003330
Fusion event
HPV-LOC105376553 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
HE574705.1;NC_001526.2;AY262282.1;HQ537777.1;EU918767.1
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
11657917/11636370 (Hg38)
End
11657917/11636370 (Hg38)
Location type
Intronic
Target gene
LOC105376553
Nearest miRNA
hsa-mir-210/Upstream/1128044; hsa-let-7a-2/Downstream/20281;
Nearest TSS
ENST00000527297/Upstream/14365; ENST00000525257/Downstream/205053;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/14098, chr11-CpG: 66/Downstream/205355
Upstream sequence
TGGGAGGGGACCCAAAGAGGGAGGGGATGCAATAGGGAGGGGGCCAGGGGTGACAAGGATTGAGGAAGGGAGAGAGGGGGGAAAAAaagcaagggatgcc
Downstream sequence
ttagaaccacatttcacagccaagggaacagaggcccagaaagggaaagtaacctgcttagggtcacacagcaccttgctcagtggagagccaggttttc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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