Basic Information
VIS ID
TVIS20003342
Fusion event
HPV-AXDND1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
HE574705.1;NC_001526.2;HQ537688.1
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
179499099/179529964 (Hg38)
End
179499099/179529964 (Hg38)
Location type
Intronic
Target gene
AXDND1
Nearest miRNA
hsa-mir-101-1/Upstream/852130; hsa-mir-1182/Downstream/273960;
Nearest TSS
ENST00000473358/Upstream/38261; ENST00000484455/Downstream/4529;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/163761, chr1-CpG: 71/Downstream/45621
Upstream sequence
gcctgccaggctgagtgggcggggcccaagcaaaactcaggtaaaggtgccaccagccatagagttttctgtccagaaaagtgacactccaaagatcccg
Downstream sequence
taacaccgctactcttcccaacctctggaaactctcagtctactctctatcttgatgagttcaattgttttaatttttagctcccacaaatgtgtgagaa
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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