Basic Information
VIS ID
TVIS20003343
Fusion event
HPV-LINC02627 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
HE574705.1;NC_001526.2;HQ537688.1
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
107499689/105739931 (Hg38)
End
107499689/105739931 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LINC02627
Nearest miRNA
hsa-mir-107/Upstream/1471526; hsa-mir-202/Downstream/5158159;
Nearest TSS
ENST00000439456/Upstream/581003; ENST00000424701/Downstream/79266;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1096877, chr10-CpG: 100/Downstream/1424091
Upstream sequence
TGGCAATTTTGTATTTTAAATGCAAATAAAGGCTCAAAATATTTCAAAATACTCTGATTAAAACCCAACAAAAATAAAATCCTCCAAATCTAGGGGAAAA
Downstream sequence
AATAAAATTTCAGGATAACTCTGTTTAATTCTATTTTTCAGCCTATATATGTATGTGGAGATTGCTTGCCATCCAACATATGTTAGGATGTCTACTGAAG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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