Basic Information
VIS ID
TVIS20003345
Fusion event
HPV-LOC284344 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
HE574705.1;NC_001526.2;HQ537688.1
Host Sequence
Chromosome
chr19
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
43748141/43243989 (Hg38)
End
43748141/43243989 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LOC284344
Nearest miRNA
hsa-mir-10395/Upstream/892784; hsa-let-7e/Downstream/1409697;
Nearest TSS
ENST00000633603/Upstream/36690; ENST00000607855/Downstream/16757;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/545828, chr19-CpG: 42/Downstream/164026
Upstream sequence
CCCCCTCCTCCCCTCCCCAGTGAGGGACATTTTTTGGTAAACCTATTTTCATTTTGGAAAATATTTATGAATAAATAGTTTTATATGACGGCTGGCAGCA
Downstream sequence
ccatctgcaaagagggacaatttgacttcctcttttcctaattgaatgccctttatttccttctcctgcctaattgccctggccagaacttccaacacta
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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