Basic Information
VIS ID
TVIS20003347
Fusion event
HPV-DPY19L1P1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
HE574705.1;NC_001526.2;HQ537688.1
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
32739199/32699587 (Hg38)
End
32739199/32699587 (Hg38)
Location type
Intronic
Target gene
DPY19L1P1
Nearest miRNA
hsa-mir-1183/Upstream/2409697; hsa-mir-10399/Downstream/33394;
Nearest TSS
ENST00000635602/Upstream/118796; ENST00000609151/Downstream/59295;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/203659, chr7-CpG: 160/Downstream/28336
Upstream sequence
tcataataatttttctagacccataaggatgttttgaggtttgaatgaggtaatctatatacagTTGAGTGCTATGGGTAGGAATAGTTGCTATTATTTT
Downstream sequence
ttgtctgcaaacagggacaatttcgcttcctcttttcctaattgaatactctttatttccttctcctgcctaattgccctggccagaacttccaacacta
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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