Basic Information
VIS ID
TVIS20003356
Fusion event
HPV-LOC107984580 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
39886282/39312145 (Hg38)
End
39886282/39312145 (Hg38)
Location type
Intronic
Target gene
LOC107984580
Nearest miRNA
hsa-mir-2276/Upstream/15149641; hsa-mir-1267/Downstream/351889;
Nearest TSS
ENST00000623511/Upstream/259073; ENST00000630730/Downstream/291026;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/273352, chr13-CpG: 75/Downstream/290567
Upstream sequence
tcttctgttaatcttggaaaccctgcaacaaccaccatgtgaaacagcctagactagctcagttgctagcccctgccaataaccaacagggaaccaaatt
Downstream sequence
gtgagtgaggatgctggctgccagctggctacaaaagcattactgagcccagccgccactaactgcaacagagatgagctgtcgtagctgaacccagccc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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