Basic Information
VIS ID
TVIS20003391
Fusion event
HPV-LINC02741 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV58
Reference genome
HQ537777.1
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
GRCh37/hg19
Start
41715305/41693755 (Hg38)
End
41715305/41693755 (Hg38)
Location type
Intronic
Target gene
LINC02741
Nearest miRNA
hsa-mir-1343/Upstream/5683551; hsa-let-7a-2/Downstream/1865901;
Nearest TSS
ENST00000527297/Upstream/233982; ENST00000530379/Downstream/18653;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/5183288, chr11-CpG: 49/Downstream/1618134
Upstream sequence
agtaaaaagcagtcaaaatggcaaatatgtgggaaaataacataatttaactttttcatCTACCATTTTTCCATCTTTAAATTGTGAATAAATAATAATc
Downstream sequence
aaagtagaaaagacctgtaatacacaggtgatcagagtatacagatggctttaacctcagtagtgaataaaaattagagttagaccaaatgttgctctgg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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