Basic Information
VIS ID
TVIS20003393
Fusion event
HPV-CNTN5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV58
Reference genome
HQ537777.1
Host Sequence
Chromosome
chr11
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
99607867/99737136 (Hg38)
End
99607867/99737136 (Hg38)
Location type
Intronic
Target gene
CNTN5
Nearest miRNA
hsa-mir-10392/Upstream/3395610; hsa-let-7a-2/Downstream/1782684;
Nearest TSS
ENST00000527297/Upstream/180990; ENST00000525236/Downstream/82396;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/716045, chr11-CpG: 64/Downstream/950056
Upstream sequence
TGTGATTTACATAGTCAGTAATGGGGGTAAGAAGAGTTAGGGGATTCCACTATTGAGAGTCATAGGAAGGGAAGGAGAGTCCTCTTTGTCTTAGATGTTA
Downstream sequence
CTGACATCTATAACTTCACTTTCTTCAAGTATTTTTGATCAATTAAGCTCTGCTTTAAGGTTTATTCTGACTACCCTCAAGGGATTGATCCTGAGCAGAC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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