Basic Information
VIS ID
TVIS20003399
Fusion event
HPV-CHD9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV58
Reference genome
HQ537777.1
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
53239751/53205839 (Hg38)
End
53239751/53205839 (Hg38)
Location type
Intronic
Target gene
CHD9
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-155-5p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-let-7e-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-22-3p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-376a-5p ; hsa-mir-181d-5p ; hsa-mir-376a-2-5p ; hsa-mir-944 ; hsa-mir-664a-3p ; hsa-mir-2052 ; hsa-mir-1193 ; hsa-mir-4262 ; hsa-mir-3607-3p ; hsa-mir-3668 ; hsa-mir-3686 ; hsa-mir-3935 ; hsa-mir-4663 ; hsa-mir-4682 ; hsa-mir-8077 ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-34b-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6794-3p ; hsa-mir-627-3p ; hsa-mir-4639-3p ; hsa-mir-342-3p ; hsa-mir-548c-3p ; hsa-mir-3163 ; hsa-mir-628-5p ; hsa-mir-7641 ; hsa-mir-3171 ; hsa-mir-139-5p
Nearest miRNA
hsa-mir-1225/Upstream/2463462; hsa-mir-11401/Downstream/3039681;
Nearest TSS
ENST00000527434/Upstream/48675; ENST00000569794/Downstream/2150;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/73913, chr16-CpG: 37/Downstream/167576
Upstream sequence
tactaaaaatgcctaaaactagccaggtgtggtggcagatgcctataatcccagccgcttgggaggctgagacaggagaatcgcttgaacccaggaagta
Downstream sequence
cagtcccaaatttcaaattgctagagatctccatttCAAACTCAGTATGAAAAGAATTAAACTTGTTATACACACATACACATTCTTTCTCAACTAGGTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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