Basic Information
VIS ID
TVIS20003437
Fusion event
HPV-MOV10L1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50576092/50137663 (Hg38)
End
50576092/50137663 (Hg38)
Location type
Intronic
Target gene
MOV10L1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-500a-5p
Nearest miRNA
hsa-let-7a-3/Upstream/174724; hsa-mir-12114/Downstream/269779;
Nearest TSS
ENST00000624155/Upstream/23205; ENST00000354853/Downstream/9302;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/46294, chr22-CpG: 49/Downstream/28323
Upstream sequence
gtgtggtggcatgtgcctgtagacctagctactcaggaggctgaggcaggagaatcgcttgaaaccaggaggtggagattgcagtgagccaagatcatgc
Downstream sequence
cactgcgctccagcctgggcgacagagcaagactctgtctcaaaaaatacatatgtatatacacatatatatattttatatatatacatatataaatata
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate