Basic Information
VIS ID
TVIS20003443
Fusion event
HPV-FAM85B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
7993613/8136091 (Hg38)
End
7993613/8136091 (Hg38)
Location type
Intronic
Target gene
FAM85B
Nearest miRNA
hsa-mir-3674/Upstream/47002; hsa-mir-10400/Downstream/912354;
Nearest TSS
ENST00000518652/Upstream/158106; ENST00000524073/Downstream/53104;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/70013, chr8-CpG: 118/Downstream/91403
Upstream sequence
agatacatattatatactgtatataaaatagaaaagtaccccaaatacatattatatactgtacacaaaatataaaattacagaaaatacatattatata
Downstream sequence
gagatggcatggacagagcccatggagaaggaggaggaaaaagagagtttggctttggttttttttttttttaagacagggtctctggctgtgtcaccca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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