Basic Information
VIS ID
TVIS20003462
Fusion event
HPV-CTB-99A3.1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
145952986/146573423 (Hg38)
End
145952986/146573423 (Hg38)
Location type
Intronic
Target gene
CTB-99A3.1
Nearest miRNA
hsa-mir-10397/Upstream/2893452; hsa-mir-103a-1/Downstream/2488890;
Nearest TSS
ENST00000502646/Upstream/10197; ENST00000503975/Downstream/26953;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/125556, chr5-CpG: 97/Downstream/304360
Upstream sequence
CTCTGATAATGTCTTCCCCATAGTTTTTATTGCAAATATCTAACAAAACTCTTATGTGATTTTTGTTATGACAACCATCAAATTGTTTTATGCCCACCTT
Downstream sequence
aagttctcatgagagctggtggttttataaggggcttccctcttcgttaggcattcattctgtctcctgtcaccctctagagaggtgccttgcaccatga
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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