Fusion event
HPV-FHIT integration
Quality evaluation
Normal
Reference genome
NC_001526.2;HQ537777.1;EU918767.1
End
60580409/60594676 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/4742082; hsa-mir-12124/Downstream/23129;
Nearest cancer related gene
Upstream sequence
CCATCAGTGGTCTCTGTCTCTTTTTGTGATCATCTTGTCATCTTTTGTGTATCTTTGTTTCTTAGACAGTGCATTTGATGGAACCCTTTTTCCTAGATCT
Downstream sequence
ttcaccagccacatgtgatgatggctgccacccttgttctagaaagcccagaatagcctctgcttcttctcatttgCATTGCTTTTTCCCCCATATCTGG
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.