Basic Information
VIS ID
TVIS20003488
Fusion event
HPV-chr1:q42.2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
230731022/230595276 (Hg38)
End
230731022/230595276 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
LINC01737 ; LOC107985357
Nearest miRNA
hsa-mir-101-1/Upstream/2133124; hsa-mir-1182/Downstream/424552;
Nearest TSS
ENST00000473358/Upstream/168785; ENST00000473671/Downstream/307;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/168320, chr1-CpG: 58/Downstream/47055
Upstream sequence
tccaggtatctgaagggataccttcaactcaaatgttgctcaactcagttttgctcaaatgtcttctcCACTGACCATATTTTAAAAATAATCAAAACAT
Downstream sequence
TATTTTTAAAGCATCATATTATCAAATTAATTTTTGTCATTTAACTTTTTATCAATAATTATTTATGTCTTCAGTCAACAAACACACTGCCCTTAATTAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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