Basic Information
VIS ID
TVIS20003504
Fusion event
HPV-chr6:q23.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
138286420/137965283 (Hg38)
End
138286420/137965283 (Hg38)
Nearest miRNA
hsa-mir-10398/Upstream/2726027; hsa-mir-1202/Downstream/469930;
Nearest TSS
ENST00000381078/Upstream/19481; ENST00000251691/Downstream/142228;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/97279, chr6-CpG: 65/Downstream/141768
Nearby gene
LOC107986545(+6739) ;
Upstream sequence
TATCCAGGGAAAAGTGACACCATTTCTATAAAGGGAACAGCACAGCTCCCTAGTTCTCCAGAGTGAGCAAGATTGTATTTAGACATGCAAAGAATCTCTG
Downstream sequence
aaaaaaaaagaaagaaaagaaagagagaaagggagaagagagaggaaggaaggaaggaaggaaagaagggagggagggaaggagggaggaagggagggga
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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