Basic Information
VIS ID
TVIS20003505
Fusion event
HPV-chr7:q22.1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
98294791/98665479 (Hg38)
End
98294791/98665479 (Hg38)
Fragile sites / regions
FRA7F
Nearest miRNA
hsa-mir-10525/Upstream/700998; hsa-mir-10399/Downstream/216171;
Nearest TSS
ENST00000635602/Upstream/45812; ENST00000417523/Downstream/182249;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/47032, chr7-CpG: 93/Downstream/203921
Nearby gene
LOC105375419(-7875) ; LOC105375418(+2741) ;
Upstream sequence
ccagacaaagtaggtcagggaagtatttccaaggaggaaaaacttggactgggtctttaacaatgactaagtgctcctcaggtagacaagttgggtgttg
Downstream sequence
cagggtcttgtaatgcagtgcacaggctgtagagcagtggtgcgaccttgactcactgcagcctccaactcctgggctccaatgaacctcccatctcagc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate